New Potential to Harness the Power of Your Immune System

Non-Relapsing Progressive MS (pMS) Cell Therapy Clinical Trial

Find a Research Site

New Hope for pMS

Treg Cell Therapy​

Treg cell therapy, like the one being studied in this clinical trial, offers new hope for non-relapsing pMS patients with progressive decline.

New Potential in pMS Treatment

targeting myelin

In pMS patients, myelin, a coating surrounding the nerves, is damaged by the body’s own immune cells. Tregs are the immune cells that naturally control inflammation and enable repair in inflamed tissue. 

 

We engineer your own Treg cells to be activated in the central nervous system (CNS), which includes your brain and spinal cord, to shut down inflammation and repair nerve injury.

How it Works

Participating in the Clinical Trial

  • Pre-Trial: Screening + Leukapheresis + Manufacturing

    Over the course of several months, using your white blood cells, we manufacture Treg cell therapy to target myelin, which is only present in the CNS (which includes your brain and spinal cord).

  • Trial: Dosing + Safety Monitoring

    Over the course of one month, you will receive back your own Tregs in an infusion. These myelin-specific Tregs will naturally circulate to the CNS and become activated.

  • Follow-up: Safety Monitoring + Followup

    You will be encouraged to participate in additional research which includes continued followup for up to 15 years.

Immune cells continuously damage myelin. Factors (green arrows) released by activated Tregs reduce myelin damage.

Join the Clinical Trial​

Harness the Power of Your Immune System to Treat pMS​

Participation Requirements

  • Ages 18+
  • Diagnosis of pMS
  • Worsening of symptoms without any pMS relapses in the past 2 years
  • Further requirements will be covered with the study team

Compensation, transportation, and lodging may be provided.

Now Enrolling

Contact Your Nearest Site TODAY

Johns Hopkins University

Baltimore, Maryland, United States, 21287

–

Alexis Kington

(667) 306-8307
Akingto1@jhmi.edu

Rutgers, Robert Wood Johnson Medical School

New Brunswick, New Jersey, United States, 08901

–

Barbara Tsounis

(732) 235-6012

bat51@rwjms.rutgers.edu

Cleveland Clinic Mellen Center

Cleveland, Ohio, United States, 44195

–

Ariel Bizon
(216) 445-9411

bizona@ccf.org

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Abata Tx 101-PMS-101_V1_111524

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