For people living with chronic hives, symptoms like itching, burning, swelling, and pain can make even simple daily activities feel unpredictable. Cold temperatures, pressure on the skin, or light scratching may trigger flare-ups that disrupt work, sleep, and overall quality of life.
Cold-induced urticaria (ColdU) and symptomatic dermographism (SD) are types of chronic inducible urticaria, meaning symptoms appear after specific triggers. While daily antihistamines are often prescribed, many individuals continue to experience uncomfortable symptoms.
The EMBARQ Study is a Phase 3 clinical trial evaluating an investigational injectable medication called barzolvolimab. Researchers are studying whether this treatment may help adults whose symptoms continue despite standard therapies. Clinical trials like EMBARQ play an important role in advancing research and offering participants the opportunity to contribute to future treatment options.
Participation is voluntary, and all studies follow strict safety regulations and ethical review processes to protect participants.