What Are Crohn’s Disease Clinical Trials?
Crohn’s disease clinical trials are research studies that test new treatments, medications, or diagnostic methods for individuals living with Crohn’s disease. These trials help determine the safety and effectiveness of innovative therapies that could improve long-term outcomes for patients.
Clinical trials are essential in advancing medical knowledge and bringing new treatment options to market—especially for chronic conditions like Crohn’s disease, which affects over half a million people in the United States alone.
Why Participate in a Clinical Trial for Crohn’s Disease?
Participating in a Crohn’s disease clinical trial offers several potential benefits:
Access to cutting-edge treatments not yet available to the general public
Close monitoring by medical professionals and researchers
Contributing to medical research that could benefit others with Crohn’s disease
No cost for treatment during the trial period in many cases
It’s important to note that all trials are voluntary, and participants can withdraw at any time.
What Types of Clinical Trials Are Available for Crohn’s Disease?
There are several categories of Crohn’s disease clinical trials, including:
Medication Trials – Testing new biologics, small molecule drugs, or biosimilars
Diet and Lifestyle Studies – Exploring the effects of diet, exercise, and probiotics
Surgical and Procedural Trials – Evaluating new surgical techniques or less invasive procedures
Observational Studies – Gathering long-term data on Crohn’s disease progression
Each trial will have specific inclusion and exclusion criteria based on age, medical history, disease severity, and prior treatments.
How to Find a Crohn’s Disease Clinical Trial Near You
If you’re interested in joining a Crohn’s clinical trial, here are some reliable resources:
ClinicalTrials.gov – Search “Crohn’s disease” + your location
Crohn’s & Colitis Foundation – Offers a clinical trial finder and support resources
Local Gastroenterology Clinics – Many private practices and academic hospitals run studies
Clinically Trials Patient Recruitment Platforms – Some organizations, like Clinically Trials, specialize in matching patients with relevant studies. Get started here.
What to Expect During a Crohn’s Clinical Trial
While each study varies, most trials follow a general structure:
Screening – You’ll undergo exams and assessments to confirm eligibility
Enrollment – Once approved, you’ll sign a consent form and begin the study
Treatment Phase – You’ll receive the investigational drug or placebo and attend regular follow-ups
Monitoring and Follow-up – Side effects, symptom changes, and lab results are carefully tracked
Most trials require regular visits over several weeks or months, with strict adherence to protocols.
Are Crohn’s Disease Clinical Trials Safe?
Yes—Crohn’s disease clinical trials are regulated by the FDA and monitored by Institutional Review Boards (IRBs) to ensure participant safety. Researchers follow strict ethical guidelines, and all risks are explained before you consent.
Final Thoughts: Should You Join a Clinical Trial?
Crohn’s disease clinical trials offer hope for better treatments and potentially long-term remission. If standard therapies haven’t worked for you—or if you’re passionate about contributing to scientific advancement—participating in a clinical trial could be a rewarding option.
Before joining, always consult with your healthcare provider and thoroughly research the trial sponsor, procedures, and potential risks
